Creative Biostructure, a biotechnology company actively working on the characterization of proteins using various techniques, recently updated its MagHelix™ Thermal Gravimetric Analysis (TGA) service for protein thermodynamics analysis to get its customers’ needs met.
TGA is a thermal analysis method in which the sample mass is measured according to time or temperature while the sample temperature is programmed in a controlled atmosphere. This analytical technique is often used to determine the composition of a sample and to predict its thermal stability.
Basically, typical applications of TGA include: Determining thermal stability-if a material (such as ceramic or polymer) is thermally stable, there will be no observed mass change; Determining oxidative stability-oxidative mass losses are the most common observable losses in TGA. Thus, it is very important to analyze the resistance to oxidation in copper alloys; Compositional analysis-temperature and weight change of decomposition reactions can allow quantitative composition analysis; Determining the purity of a mineral, inorganic compound, or organic material; Measuring the weight of fiberglass and inorganic fill materials in laminates, plastics, paints and composite materials; Determining water/carbon content or other residual solvents in a material; Allowing analysis of reactions with air, oxygen, or other reactive gases; and enhancing product formulation processes or ensuring product safety.
Through TGA analysis, Creative Biostructure provides information about chemical phenomena and physical phenomena, including chemisorption, dehydration, decomposition, solid gas reactions (such as oxidation or reduction), vaporization, sublimation, absorption and desorption. Essentially, TGA can assess samples that have lost or increased weight due to decomposition, oxidation, or dehydration.
According to the information on Creative Biostructure’s official website, TGA instruments can be utilizied to ramp temperature from room temperature to 1000°C in different gas atmospheres such as nitrogen, air or other inert gases. In addition, sample weight can range from 1 mg to 150 mg, and the sensitivity of weight change is 0.01 mg.
Now, MagHelix™ analytical methods for biophysical characterization of biomolecules at Creative Biostructure include but are not limited to:
Surface Plasmon Resonance
Isothermal Titration Calorimetry
Differential Scanning Calorimetry
Bio-Layer Interferometry (BLI) Technology
“During the past years, we have been working on the characterization of proteins using a variety of techniques, as well as the engineering of proteins for various applications. The extensive experience got from those area enables us to provide customized, cost-effective, and quality services timely.” Commented Joanna, the official speaker from Creative Biostructure.
More information about MagHelix™ Thermal Gravimetric Analysis (TGA) at Creative Biostructure can be viewed here: https://www.creative-biostructure.com/maghelix%E2%84%A2-thermal-gravimetric-analysis-tga-216.htm.
About Creative Biostructure
With our advanced platform and equipment, our coronavirus research team can help researchers perform basic research on coronavirus-related bioinformatics analysis, viral particle identification and characterization, protein structure analysis, and protein interaction analysis. We also offer structure-based antiviral drug discovery and pre-clinical vaccine development services.